Eight years of wind and rain, triple quadrupole mass spectrometry ushered in a new era of domestic mass spectrometry

[ Instrument Network Instrument Development ] On July 10, 2019, the first major scientific instrument and equipment development project in 2011, the first batch of start-up projects - "Development of triple quadrupole tandem mass spectrometry system and its application in trace organic matter analysis (2011YQ060084 The comprehensive acceptance meeting was held in Hangzhou, Zhejiang Province. Experts from the Chinese Academy of Sciences, such as Academician Chai Zhifang, formed the project comprehensive acceptance expert group, and conducted comprehensive acceptance according to the report content of the project.
The acceptance meeting was hosted by the Science and Technology Evaluation Center of the Ministry of Science and Technology, and the Science and Technology Department of the Ministry of Ecology and Environment organized the Science and Technology Department of the Ministry of Ecology and Environment. The researcher of the China-Japan Friendship Environmental Protection Center (National Environmental Analysis and Testing Center) conducted a project report, and the comprehensive acceptance expert group guided the meeting. Review. The expert group examined and accepted the project acceptance materials, the completion of the project objectives, the completion of the project evaluation indicators, the application and promotion of the project results, the role of engineering and industrialization.
After listening to reports, data review, production line field visits and inquiries, the members of the expert group conducted in-depth discussions on the project-related situation, and agreed that the project acceptance materials were complete, and the overall compliance with the acceptance requirements, the research results reached the assessment indicators in the task book, and With engineering and industrialization capabilities, it is unanimously agreed to pass the acceptance.
Background of the project
The project is led by the China-Japan Friendship Environmental Protection Center (National Environmental Analysis and Testing Center). The research and development team of Hangzhou Spectrum Education Technology Development Co., Ltd. (hereinafter referred to as “Puyu Technology”) undertook the research and development and industrialization of the project. Participating units include Tsinghua University, China Institute of Metrology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Research Center for Eco-Environmental Sciences of the Chinese Academy of Sciences, Zhejiang Provincial Center for Disease Control and Prevention, and Beijing Proteome Research Center.
This special project focuses on the national “Twelfth Five-Year” scientific and technological development plan, and develops triple quadrupole tandem mass spectrometry system products and supporting automatic pretreatment devices and other high-throughput, high-sensitivity and automatic detection requirements for complex organic compounds in complex systems. Key components, development of trace organic matter analysis platform based on triple quadrupole tandem mass spectrometry system, research and application demonstration in environmental monitoring, environmental ecotoxicology, food safety and proteomics, to achieve triple quadrupole connection Localization and industrialization of mass spectrometry systems.
Subject content
The technology research and development technical team of the spectrum technology is responsible for the research and development and industrialization of the triple quadrupole mass spectrometer in the project. It has overcome the cores of high-stability electrospray ion source technology, high-speed collision cell technology, RF drive power technology, and tandem mass spectrometry. Technology; developed triple quadrupole mass spectrometer control analysis software and data analysis software; developed a highly selective, highly sensitive and high-throughput triple quadrupole mass spectrometer product with independent intellectual property rights, established a planned production line, realized Mass production and sales.
Application result
The prototype of the triple quadrupole mass spectrometer has been provided to the China-Japan Friendship Environmental Protection Center, the Zhejiang Provincial Center for Disease Control and Prevention, the Chinese Academy of Sciences Ecological Environment Research Center and the Beijing Proteome Research Center for application testing, and has been well received by the testing unit. Completed the application methods of four types of samples in the environmental field, food safety field, ecological environment DNA damage and proteomics, and formed 4 applications covering ecological toxicology, proteomics, environmental monitoring and food safety. The demonstration base has achieved breakthroughs in the fields of clinical medical testing and disease diagnosis.
The implementation of this special project accelerated the pace of localization of the triple quadrupole mass spectrometer, which effectively promoted the advancement of the technical level of China's high-end analytical instrument industry, broke the monopoly of foreign products in this field, realized import substitution, and promoted Scientific research in many fields such as environmental monitoring, environmental ecotoxicology, food safety and proteomics.
As a high-end mass spectrometry instrument manufacturer, Spectrum Technology is determined to be the promoter of future laboratory explorers and high-end analytical instruments. Next, Spectrum Education will continue to adhere to the in-depth research and development based on user needs, serve Chinese users, and make due contributions to the realization of the Chinese dream in the field of high-end analytical instruments.
(Original title: 8 years of wind and rain, triple quadrupole mass spectrometry ushered in a new era of domestic mass spectrometry)

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