Bio 3D printer weak bio-printing pen BioPen come out

Biological 3D printing technology is always making people clap, whether it can survive for dozens of days of 3D printing of cerebral cortex tissue, or transplanted to mice who 3D printed ovaries, often makes people feel weird. Recently, the researchers at the University of Wollongong in Australia have even developed a biological 3D printing pen, which is simply the 3Doodler in the biological world.

Known as the BioPen, this pens is amazing because doctors can "draw" the cells directly on the patient's damaged bone or cartilage tissue with a pen during surgery.

How is this all done? It is understood, BioPen contains biological ink containing stem cells inside, they are wrapped in biopolymer, such as alginate (a seaweed extract), the outside by a layer of hydrogel protection. These inks can be squeezed directly onto the bones and solidified by a pen-shaped UV lamp. These stem cells then multiply in the body and separate from nerves, muscles, and bone cells, eventually forming tissue.

To some extent, this study has a transformative effect on the repair of cartilage surgery. After cartilage tissue injury, it is often difficult to determine exactly which shape of artificial cartilage to implant, and now only BioPen will be damaged site Fill, cartilage tissue can be self-healing.

In addition, the solution can be further tailored to a customized model, coupled with specific medications to promote recovery and growth. It is understood that the current prototype of BioPen is made of medical grade plastic and titanium 3D printing, light weight and conducive to disinfection.

Researcher Choong (L), Wallace

To date, the viability of cells extruded from the 3D Pens BioPen has been above 97%, and the later complete report will be published in the journal Biofabrication.

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